đ
14 April 2026
DOI: 10.26877/bioma.v15i1.3070
PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF SOFT CORAL Nephthea sp. EXTRACT ISOLATED AGAINST Escherichia coli
Bioma : Jurnal Ilmiah Biologi
Universitas Persatuan Guru Republik Indonesia Semarang
đ Abstract
This study aimed to evaluate the antibacterial potential of Nephthea sp. extract against Escherichia coli and to analyze the phytochemical constituents present in Nephthea sp. using various solvents. The extraction process was carried out using the maceration method with three different solvents: n-hexane, ethyl acetate, and methanol. The resulting extracts were analyzed through phytochemical screening and antibacterial activity assays. The results showed that Nephthea sp. extract contained several classes of bioactive metabolites, including alkaloids, flavonoids, triterpenoids, steroids, tannins, and saponins. Antibacterial testing demonstrated that the ethyl acetate extract produced the largest inhibition zone, measuring 3.16 mm. Based on the ANOVA test results, the 25% concentration showed a significant effect on the inhibition zone. Based on phytochemical analysis, the ethyl acetate extract contained triterpenoid compounds, whereas the other solvents did not
đ Keywords
#soft coral; antibacterial activity; phytochemical; Nephthea sp.; sequential maceration
âšī¸ Informasi Publikasi
Tanggal Publikasi
14 April 2026
Volume / Nomor / Tahun
Tahun 2026
đ HOW TO CITE
Setyaningrum, Tri Wahyu; Nurulfadilah; Candri, Dining Aidil ; Dharmayani, Ni Komang Tri ; Ghazali, Mursal; Faturrahman, "PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF SOFT CORAL Nephthea sp. EXTRACT ISOLATED AGAINST Escherichia coli," Bioma : Jurnal Ilmiah Biologi, Apr. 2026.
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