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Menampilkan 1–10 dari 502 artikel
Low-Dose Salinomycin Targets Multidrug Resistance via P-Glycoprotein and NF-κB in Osteosarcoma Cells
Ayu, Onarisa
; Rusda, Muhammad
; Sembiring, Rosita Juwita
; Nasution, Iqbal Pahlevi Adeputra
; Mahyudin, Ferdiansyah
; Amin, Mustafa Mahmud
; Pasaribu, Hotma Partogi
; Tobing, Tina Christina Lumban
Chemotherapy resistance in osteosarcoma remains a major clinical obstacle, largely driven by drug efflux mechanisms mediated by P-glycoprotein (ACBC1/ABCB1) and activation of NF-κB signaling (NFKB1). This study investigated the potential of Salinomycin to modulate these multidrug resistance–associated genes in U2OS osteosarcoma cells and explore its role in overcoming chemoresistance. A true experimental post-test-only control group design was used. U2OS cells were treated with varying concentra...
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Effect of Perceptual Motor Program Combined with Obstacle Course Exercise on Dynamic Balance in Children with Autism Spectrum Disorders
Devi, An-nissa Istifarra Koestya
; Ramadhani, Alinda Nur
; Mirawati, Dita
; Agustyaningsih, Nugraheni
FISIO MU: Physiotherapy Evidences
Vol 7
, No 2
(2026)
Introduction: Disorders of the neuromuscular system in children with autism cause motor deficits which cause children with autism to be unable to move. This is caused by a decrease in postural tone. Disturbed postural tone in children with autism will also cause coordination disorders and abnormal movement patterns. Apart from that, improper postural control in children with autism will cause changes in balance and balance disorders. For this reason, researchers provide Perceptual Motor Program...
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Technology-Driven Digital Marketing Strategies and their Impact on E-commerce Purchase Decisions
The rapid growth of internet penetration and digital platforms has transformed marketing practices in Indonesian Vocational Training Centers (LPKs). However, inconsistent outcomes in trainee recruitment highlight a gap in understanding the effectiveness of digital marketing in this context. This study aims to examine the effect of digital marketing on purchase intention, with consumer engagement as a mediator and consumer trust as a moderator. Data were collected from 384 trainees in East and We...
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Building Financial Resilience of Boarding House Employees Through Financial Literacy
Inflation and post-COVID-19 economic uncertainty have placed significant financial pressure on low-income workers, including boarding house employees. This study aims to analyze the effects of financial literacy, financial attitude, and economic pressure on personal financial management behavior and financial resilience among boarding house employees in Semarang Regency. A mixed-methods sequential explanatory approach was employed, with the quantitative phase (n=150) analyzed using PLS-SEM, foll...
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Skrining Tekanan Darah Sebagai Upaya Pencegahan Hipertensi di Posyandu Kenanga 1 Desa Bendan
Natalia Novel, Desi
; Dhuha, Ahad Agafian
; Vionyca, Faureladinda
; Yumna, Destya Ashila
; Nanda, Evilia
; Purnama, Ghafari Surya
; Fathurrohman, Muhammad
Jurnal Inovasi dan Pengabdian Masyarakat Indonesia
Vol 5
, No 2
(2026)
Latar Belakang: Hipertensi merupakan kondisi meningkatnya tekanan darah di atas batas normal dan menjadi salah satu penyebab utama penyakit kardiovaskular. Rendahnya kesadaran masyarakat dalam melakukan pemeriksaan tekanan darah secara rutin menjadikan hipertensi sebagai “silent killer” yang berbahaya. Tujuan: Untuk mengidentifikasi hipertensi melalui skrining tekanan darah dan memberikan informasi kesehatan sebagai upaya pencegahan dan pengendalian hipertensi. Metode: Kegiatan pengabdian kepada...
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Overview of Public Safety Center (PSC) 119 Call Patterns in Semarang City in 2024 as a Basis for Strengthening the Emergency Response System
Ramadhani, Salma Aulia
; Febriyanti, Anisya Ayu
; Agung Nugroho, Muhammad Farhan
; Tunggal Djaja, Melinda Valerie
; Nurhayati Loleh, Jevita Sri
; Wulandari, Respati
; Zaini, Ahmad
; Wardana, Wisnu
; Anggraini, Ira
; Handayani, Rustiyana Wuri
VISIKES
Vol 25
, No 1
(2026)
The Public Safety Center (PSC) 119 service is an integrated emergency medical system that plays a crucial role in Indonesia's pre-hospital healthcare system. The demand pattern for PSC-119 services can be influenced by various factors, including weather conditions and community mobility. In Semarang City, no research has described the weekly trends of PSC-119 calls based on case types and their relationship with weather parameters. This study aims to describe the weekly trend patterns of PSC-119...
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Tantangan Desentralisasi Fiskal Era UU HKPD: Tinjauan Kepustakaan atas Implikasi Resistensi Wajib Pajak Kendaraan Bermotor terhadap Kapasitas Keuangan Kota Semarang
Zidni Muntaha Ridho
; Nayzilla Mega Rahmadhani
; Aisyah Nur Fadila
; Kharisma Ilmi Alawy Wahbiyah
; Dewi Arimbi Burhandani Piliang
; Beryl Shira Filiandri
; Risma Tria Syahrani
; Melda Fadiyah Hidayat
; Revienda Anita Fitrie
DHARMA EKONOMI
(2026)
The implementation of regional autonomy and fiscal decentralization aims to enhance local governments' financial independence. However, fiscal imbalances between the central and regional governments led to the enactment of Law Number 1 of 2022 (UU HKPD), designed to strengthen regional fiscal capacity. This law introduces a piggyback tax system through a surcharge on the Motor Vehicle Tax. This study analyzes the dynamics of the piggyback tax system in Semarang City, focusing on the implications...
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Characteristics of Sweet Bread with Substitution of Mocaf Flour and Variation of Cilembu Sweet Potato and Yellow Pumpkin Puree
Agrobioteknologi
(2026)
Bread is a food that is favored by various groups of people. Wheat flour is the main raw material in making sweet bread. Wheat flour is made from wheat, to reduce wheat imports, wheat flour needs to be replaced with other alternative ingredients. Cilembu sweet potato is one of the sweet potato plants that has the potential to be developed in Indonesia because it is abundant and has good nutritional content. Sweet potato cilembu contain high beta carotene that can be used as a functional food. Pu...
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Implementasi Sistem Manajemen Inventori dan Aset REA TEHNIK Berbasis Web Menggunakan Framework Laravel
Ramadhan, Aditya Ilham
; Devi, Putri Aisyiyah Rakhma
; Ramadhan, Aditya Ilham
; Devi, Putri Aisyiyah Rakhma
JUISI : Jurnal Ilmiah Sistem Informasi
Vol 30
, No 2
(2026)
Mekanisme administrasi barang pada REA TEHNIK sebelumnya masih mengandalkan cara-cara konvensional melalui pencatatan fisik serta bantuan perangkat lunak Microsoft Excel. Namun, pola kerja tersebut memicu sejumlah hambatan praktis, di antaranya lambatnya akses terhadap informasi stok, risiko diskrepansi data akibat kelalaian input, hingga birokrasi validasi laporan yang memakan waktu lama [1], [2]. Keterbatasan ini mendasari urgensi pengembangan sebuah platform digital yang terintegrasi dan bers...
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Characteristics of Garlic Crackers with Soy Flour Substitution (Glycine max. L) and Variations of Katuk Leaf Extract (Sauropus androgynus L)
Agrobioteknologi
(2026)
Garlic crackers are a snack made of starch-based ingredient with the addition of spices and leavening agents. In this study, garlic crackers were made with variations of tapioca flour, soy flour, and katuk leaf extract. Soy flour and katuk leaf extract were added to increase the nutritional value, especially to increase the protein and fiber content. This research aimed to formulate garlic crackers that will be preferred by the consumer and to determine the chemical, physical, and organoleptic p...
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