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Menampilkan 21–30 dari 2324 artikel
Low-Dose Salinomycin Targets Multidrug Resistance via P-Glycoprotein and NF-κB in Osteosarcoma Cells
Ayu, Onarisa
; Rusda, Muhammad
; Sembiring, Rosita Juwita
; Nasution, Iqbal Pahlevi Adeputra
; Mahyudin, Ferdiansyah
; Amin, Mustafa Mahmud
; Pasaribu, Hotma Partogi
; Tobing, Tina Christina Lumban
Chemotherapy resistance in osteosarcoma remains a major clinical obstacle, largely driven by drug efflux mechanisms mediated by P-glycoprotein (ACBC1/ABCB1) and activation of NF-κB signaling (NFKB1). This study investigated the potential of Salinomycin to modulate these multidrug resistance–associated genes in U2OS osteosarcoma cells and explore its role in overcoming chemoresistance. A true experimental post-test-only control group design was used. U2OS cells were treated with varying concentra...
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Exploring Serum Bilirubin as a Potential Biomarker for Primary Open-Angle Glaucoma
Total bilirubin (TBIL) functions as a natural antioxidant, and its levels tend to decrease with increasing oxidative stress, including in glaucoma tissue. This study aims to explore the relationship between total serum bilirubin levels and the severity of primary open-angle glaucoma (POAG). A total of 25 POAG patients and 25 control subjects further divided into aged >60 years and ≤60 years from the Glaucoma Clinic of the Universitas Sumatera Utara Hospital and its affiliated hospitals were i...
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Evaluating Behavior-Driven Metrics in Gamified Hybrid Environments: A Structural Analysis Approach
Henka Bayu Seta
; Zatin Niqotaini
; Sarika Afrizal
; Theresiawati
; Artika Arista
; Rapolo Joshua Napitupulu
; Muhammad Ibrahim Al Farisi
Despite the widespread adoption of gamification in higher education, a significant research gap remains regarding the structural pathways through which specific game elements influence psychological drivers and academic success in hybrid settings. This study addresses this by evaluating the impact of badges, points, progress bars, and leaderboards on student motivation and outcomes using a quantitative approach with a sample of 437 university students in Indonesia. Data were analyzed using Parti...
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Student academic hardiness: descriptive analysis and its relationship with individual characteristic
Harahap, Ade Chita Putri
; Indreswari, Henny
; Hidayah, Nur
; Setyowati, Arbin Janu
; Ramli, M
; Makhsin, Mardzelah Binti
; Harahap, Dinda Permatasari
; Simarmata, Sari Wardani
This study aims to analyze students' academic hardiness and examine its differences based on individual characteristics as well as its relationship with academic achievement. This research employed a quantitative approach with a descriptive and correlational design. The participants consisted of 103 students selected using accidental sampling. Data were collected using a Likert-scale questionnaire measuring the dimensions of commitment, control, and challenge. Data analysis was conducted using d...
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The effect of spiritual well-being on career anxiety among students
Career anxiety among university students is commonly associated with external factors such as job readiness and environmental pressure. However, the role of internal aspects, particularly spiritual well-being, has not been widely explored. In fact, an individual’s ability to find meaning in life and deal with uncertainty may influence their level of anxiety. This study aims to examine the effect of spiritual well-being on career anxiety among students across different semesters. This study emplo...
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The effect of role playing on social interaction
This research was motivated by the results of observations that found a number of students were still unable to interact optimally. Some students tend to be solitary, show awkwardness when dealing with new friends, lack courage in communicating, and have difficulty working together with peers outside their circle of friends and are reluctant to get involved in group activities. This study aims to determine the influence of role playing on social interaction. Researchers use group guidance servic...
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AROMATERAPI MINYAK PAPPERMINT SEBAGAI TERAPI KOMPLEMENTER DALAM MENGURANGI MUAL DAN MUNTAH PADA IBU HAMIL
Mual dan muntah pada ibu hamil (emesis gravidarum) merupakan keluhan umum pada trimester pertama yang dapat menurunkan kualitas hidup dan berisiko menimbulkan komplikasi jika tidak ditangani dengan tepat. Terapi farmakologis sering menimbulkan kekhawatiran terkait efek samping bagi janin, sehingga pengobatan komplementer seperti aromaterapi menjadi alternatif yang banyak diminati. Penelitian ini bertujuan untuk mengkaji secara sistematis bukti ilmiah mengenai efektivitas aromaterapi minyak peppe...
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Technology-Driven Digital Marketing Strategies and their Impact on E-commerce Purchase Decisions
The rapid growth of internet penetration and digital platforms has transformed marketing practices in Indonesian Vocational Training Centers (LPKs). However, inconsistent outcomes in trainee recruitment highlight a gap in understanding the effectiveness of digital marketing in this context. This study aims to examine the effect of digital marketing on purchase intention, with consumer engagement as a mediator and consumer trust as a moderator. Data were collected from 384 trainees in East and We...
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Design and Implementation of a Web-Based QR Code Employee Attendance System for Optimizing Attendance Management: A Case Study at Bento and Es Teh Luwes Ungaran
Nufninu, Novinda Grezen
; Rudjiono, Rudjiono
; Panjaitan, Cherlina Helena Purnamasari
; Nufninu, Novinda Grezen
; Rudjiono, Rudjiono
; Panjaitan, Cherlina Helena Purnamasari
Penelitian ini dilatarbelakangi oleh proses absensi karyawan pada Stand Bento dan Stand Es Teh Luwes Ungaran yang masih dilakukan secara manual menggunakan buku absensi. Kondisi tersebut menimbulkan beberapa kendala, seperti kesalahan pencatatan jam masuk dan pulang, risiko kehilangan atau kerusakan data, serta lambatnya proses rekapitulasi laporan kehadiran. Penelitian ini bertujuan untuk merancang dan mengimplementasikan sistem absensi karyawan berbasis web menggunakan teknologi QR Code guna m...
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Analisis Perbandingan Yolov11 dan MobileNetV3 untuk Klasifikasi Varietas Padi
Octaviansyah, Ade
; Sari, Herva Emilda
; Raharjo, Teguh
; Octaviansyah, Ade
; Sari, Herva Emilda
; Raharjo, Teguh
JUISI : Jurnal Ilmiah Sistem Informasi
Vol 17
, No 1
(2026)
Penelitian ini bertujuan untuk menganalisis dan membandingkan kinerja model YOLOv11 dan MobileNetV3 dalam mengklasifikasikan varietas padi berdasarkan gambar digital. Kumpulan data terdiri dari 10.000 gambar yang mewakili lima varietas padi, yaitu Arborio, Basmati, Ipsala, Jasmine, dan Karacadag. Kumpulan data tersebut dibagi menjadi set pelatihan dan set pengujian, dengan proses pelatihan dilakukan selama 100 epoch. Hasil evaluasi menunjukkan bahwa MobileNetV3 mencapai akurasi klasifikasi sebes...
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